Yes, you can cut Port Saint Laurent Marble with a tile cutter. However, it is important to note that marble is a natural stone and can be brittle, so it may be more difficult to cut compared to other types of tile. It is recommended to use a wet saw or a diamond blade to ensure a clean and precise cut without causing any damage to the marble. It is also advisable to wear safety goggles and gloves when cutting marble to protect yourself from any flying debris.